PURPLE

note

A purity, ploidy and copy number estimator for whole genome tumor data.

https://github.com/hartwigmedical/hmftools/

DOI: 10.1038/s41586-019-1689-y

GNU General Public License v3.0

PURPLE combines B-allele frequency (BAF), read depth ratios, somatic variants and structural variant breakpoints to estimate the purity and copy number profile of a tumor sample, and also predicts gender, the MSI status, tumor mutational load and burden, clonality and the whole genome duplication status.

File search patterns

purple/purity:
  fn: '*.purple.purity.tsv'
purple/qc:
  fn: '*.purple.qc'